diff --git a/CHANGES.md b/CHANGES.md
index 70e1f76..23aa2bb 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -41,12 +41,16 @@ https://github.com/nimterop/nimterop/compare/v0.5.9...v0.6.3
 
 - `xxxJBB` now allows for customizing the base location to search packages with the `jbbFlags` param to `getHeader()`. Specifying `giturl=xxx` where `xxx` could be a full Git URL or just the username for Github.com allows changing the default Git repo. In addition, `url=xxx` is also supported to download project info and binaries compiled with BinaryBuilder.org but hosted at another non-Git location. (since v0.6.3)
 
+- It is now possible to exclude the contents of specific files or entire directories from the wrapped output using `--exclude | -X` with `toast` or `cExclude()` from a wrapper. This might be required when a header uses `#include` to pull in external dependencies. E.g. `sciter` has a `#include <gtk/gtk.h>` which pulls in the entire GTK ecosystem which is needed for successful preprocessing but we do not want to include those headers in the wrapped output when using `--recurse | -r`.
+
 ### Other improvements
 
 - Generated wrappers no longer depend on nimterop being present - no more `import nimterop/types`. Supporting code is directly included in the wrapper output and only when required. E.g. enum macro is only included if wrapper contains enums. [#125][i125] (since v0.6.1)
 
 - `cImport()` now includes wrapper output from a file rather than inline. Errors in generated wrappers will no longer point to a line in `macros.nim` making debugging easier. (since v0.6.1)
 
+- `cIncludeDir()` can now accept a `seq[string]` of directories and an optional `exclude` param which sets those include directories to not be included in the wrapped output.
+
 
 ## Version 0.5.0
 
diff --git a/README.md b/README.md
index f9e9307..0e79a6f 100644
--- a/README.md
+++ b/README.md
@@ -132,6 +132,7 @@ cDefine("HAS_ABC")            # Set #defines for preprocessor and compiler
 cDefine("HAS_ABC", "DEF")
 
 cIncludeDir("clib/include")   # Setup any include directories
+cExclude("clib/file.h")       # Exclude file from wrapped output
 
 cImport("clib.h")             # Generate wrappers for header specified
 
@@ -219,6 +220,7 @@ Options:
   -d, --debug          bool      false    enable debug output
   -D=, --defines=      strings   {}       definitions to pass to preprocessor
   -l=, --dynlib=       string    ""       {.dynlib.} pragma to import symbols - Nim const string or file path
+  -X=, --exclude=      strings   {}       files or directories to exclude from the wrapped output
   -f=, --feature=      Features  {}       flags to enable experimental features
   -I=, --includeDirs=  strings   {}       include directory to pass to preprocessor
   -m=, --mode=         string    ""       language parser: c or cpp
diff --git a/nimterop/cimport.nim b/nimterop/cimport.nim
index cedd903..95004ad 100644
--- a/nimterop/cimport.nim
+++ b/nimterop/cimport.nim
@@ -120,6 +120,9 @@ proc getToast(fullpaths: seq[string], recurse: bool = false, dynlib: string = ""
   for i in gStateCT.includeDirs:
     cmd.add &" --includeDirs+={i.sanitizePath}"
 
+  for i in gStateCT.exclude:
+    cmd.add &" --exclude+={i.sanitizePath}"
+
   if not noNimout:
     cmd.add &" --pnim"
 
@@ -415,21 +418,52 @@ proc cAddSearchDir*(dir: string) {.compileTime.} =
   if dir notin gStateCT.searchDirs:
     gStateCT.searchDirs.add(dir)
 
-macro cIncludeDir*(dir: static string): untyped =
+macro cIncludeDir*(dirs: static seq[string], exclude: static[bool] = false): untyped =
+  ## Add include directories that are forwarded to the C/C++ preprocessor if
+  ## called within `cImport()` or `c2nImport()` as well as to the C/C++
+  ## compiler during Nim compilation using `{.passC: "-IXXX".}`.
+  ##
+  ## Set `exclude = true` if the contents of these include directories should
+  ## not be included in the wrapped output.
+  for dir in dirs:
+    var dir = interpPath(dir)
+    result = newNimNode(nnkStmtList)
+
+    let fullpath = findPath(dir)
+    if fullpath notin gStateCT.includeDirs:
+      gStateCT.includeDirs.add(fullpath)
+      if exclude:
+        gStateCT.exclude.add(fullpath)
+      let str = &"-I{fullpath.quoteShell}"
+      result.add quote do:
+        {.passC: `str`.}
+      if gStateCT.debug:
+        gecho result.repr
+
+macro cIncludeDir*(dir: static[string], exclude: static[bool] = false): untyped =
   ## Add an include directory that is forwarded to the C/C++ preprocessor if
   ## called within `cImport()` or `c2nImport()` as well as to the C/C++
   ## compiler during Nim compilation using `{.passC: "-IXXX".}`.
-  var dir = interpPath(dir)
-  result = newNimNode(nnkStmtList)
+  ##
+  ## Set `exclude = true` if the contents of this include directory should
+  ## not be included in the wrapped output.
+  return quote do:
+    cIncludeDir(@[`dir`], `exclude` == 1)
 
-  let fullpath = findPath(dir)
-  if fullpath notin gStateCT.includeDirs:
-    gStateCT.includeDirs.add(fullpath)
-    let str = &"-I{fullpath.quoteShell}"
-    result.add quote do:
-      {.passC: `str`.}
-    if gStateCT.debug:
-      gecho result.repr
+macro cExclude*(paths: static seq[string]): untyped =
+  ## Exclude specified paths - files or directories from the wrapped output
+  ##
+  ## Full path to file or directory is required.
+  result = newNimNode(nnkStmtList)
+  for path in paths:
+    gStateCT.exclude.add path
+
+macro cExclude*(path: static string): untyped =
+  ## Exclude specified path - file or directory from the wrapped output.
+  ##
+  ## Full path to file or directory is required.
+  return quote do:
+    cExclude(@[`path`])
 
 proc cAddStdDir*(mode = "c") {.compileTime.} =
   ## Add the standard `c` [default] or `cpp` include paths to search
diff --git a/nimterop/globals.nim b/nimterop/globals.nim
index 17b9518..89e403f 100644
--- a/nimterop/globals.nim
+++ b/nimterop/globals.nim
@@ -19,6 +19,7 @@ type
     debug*: bool               # `cDebug()` or `--debug | -d` to enable debug mode
     defines*: seq[string]      # Symbols added by `cDefine()` and `--define | -D` for C/C++ preprocessor/compiler
     dynlib*: string            # `cImport(dynlib)` or `--dynlib | -l` to specify variable containing library name
+    exclude*: seq[string]      # files or directories to exclude from the wrapped output
     feature*: seq[Feature]     # `--feature | -f` feature flags enabled
     includeDirs*: seq[string]  # Paths added by `cIncludeDir()` and `--includeDirs | -I` for C/C++ preprocessor/compiler
     mode*: string              # `cImport(mode)` or `--mode | -m` to override detected compiler mode - c or cpp
diff --git a/nimterop/toast.nim b/nimterop/toast.nim
index 1cda239..20dc79e 100644
--- a/nimterop/toast.nim
+++ b/nimterop/toast.nim
@@ -13,7 +13,7 @@ var
   preMainOut = ""
 
 proc process(gState: State, path: string) =
-  doAssert existsFile(path), &"Invalid path {path}"
+  doAssert fileExists(path), &"Invalid path {path}"
 
   if gState.mode.Bl:
     gState.mode = getCompilerMode(path)
@@ -38,6 +38,7 @@ proc main(
     debug = false,
     defines: seq[string] = @[],
     dynlib: string = "",
+    exclude: seq[string] = @[],
     feature: seq[Feature] = @[],
     includeDirs: seq[string] = @[],
     mode = "",
@@ -65,6 +66,7 @@ proc main(
     debug: debug,
     defines: defines,
     dynlib: dynlib,
+    exclude: exclude,
     feature: feature,
     includeDirs: includeDirs,
     mode: mode,
@@ -222,6 +224,7 @@ when isMainModule:
     "debug": "enable debug output",
     "defines": "definitions to pass to preprocessor",
     "dynlib": "{.dynlib.} pragma to import symbols - Nim const string or file path",
+    "exclude": "files or directories to exclude from the wrapped output",
     "feature": "flags to enable experimental features",
     "includeDirs": "include directory to pass to preprocessor",
     "mode": "language parser: c or cpp",
@@ -247,6 +250,7 @@ when isMainModule:
     "debug": 'd',
     "defines": 'D',
     "dynlib": 'l',
+    "exclude": 'X',
     "feature": 'f',
     "includeDirs": 'I',
     "noComments": 'c',
diff --git a/nimterop/toastlib/getters.nim b/nimterop/toastlib/getters.nim
index 1e70d59..8c6abe1 100644
--- a/nimterop/toastlib/getters.nim
+++ b/nimterop/toastlib/getters.nim
@@ -286,7 +286,16 @@ proc getKeyword*(kind: NimSymKind): string =
 proc getCurrentHeader*(fullpath: string): string =
   ("header" & fullpath.splitFile().name.multiReplace([(".", ""), ("-", "")]))
 
+proc isIncluded(gState: State, file: string): bool {.inline.} =
+  # Check if the specified file should be excluded from wrapped output
+  if gState.exclude.nBl:
+    for excl in gState.exclude:
+      if file.startsWith(excl):
+        return
+  result = true
+
 proc getPreprocessor*(gState: State, fullpath: string) =
+  # Get preprocessed output from the C/C++ compiler
   var
     args: seq[string]
     start = false
@@ -332,14 +341,15 @@ proc getPreprocessor*(gState: State, fullpath: string) =
           start = true
         elif gState.recurse:
           if (pDir.Bl or pDir in line) and line notin gState.headersProcessed:
-            start = true
             newHeaders.incl line
+            start = gState.isIncluded(line)
           else:
             for inc in includeDirs:
               if line.startsWith(inc) and line notin gState.headersProcessed:
-                start = true
                 newHeaders.incl line
-                break
+                start = gState.isIncluded(line)
+                if start:
+                  break
       elif ": fatal error:" in line:
         doAssert false,
           "\n\nFailed in preprocessing, check if `cIncludeDir()` is needed or compiler `mode` is correct (c/cpp)" &