diff --git a/Doc/Manual/Preprocessor.html b/Doc/Manual/Preprocessor.html
index 5afa59243..2dd79dac5 100644
--- a/Doc/Manual/Preprocessor.html
+++ b/Doc/Manual/Preprocessor.html
@@ -102,8 +102,6 @@ by SWIG when it is parsing the interface:
 <div class="code"><pre>
 SWIG                            Always defined when SWIG is processing a file
 SWIGIMPORTED                    Defined when SWIG is importing a file with <tt>%import</tt>
-SWIGMAC                         Defined when running SWIG on the Macintosh
-SWIGWIN                         Defined when running SWIG under Windows
 SWIG_VERSION                    Hexadecimal number containing SWIG version,
                                 such as 0x010311 (corresponding to SWIG-1.3.11).
 
diff --git a/Source/Modules/main.cxx b/Source/Modules/main.cxx
index 30d12f26b..4903416cd 100644
--- a/Source/Modules/main.cxx
+++ b/Source/Modules/main.cxx
@@ -844,12 +844,6 @@ int SWIG_main(int argc, char *argv[], Language *l) {
 
   Preprocessor_define((DOH *) "SWIG 1", 0);
   Preprocessor_define((DOH *) "__STDC__", 0);
-#ifdef MACSWIG
-  Preprocessor_define((DOH *) "SWIGMAC 1", 0);
-#endif
-#ifdef SWIGWIN32
-  Preprocessor_define((DOH *) "SWIGWIN32 1", 0);
-#endif
 
   // Set the SWIG version value in format 0xAABBCC from package version expected to be in format A.B.C
   String *package_version = NewString(PACKAGE_VERSION); /* Note that the fakeversion has not been set at this point */